Educational activities

Presentations by the Expanded Access Program for Convalescent Plasma team.

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Sample data form used by the Expanded Access Program for Convalescent Plasma team.

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Articles authored by the Expanded Access Program for Convalescent Plasma team.

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EAP for Convalescent Plasma

Expanded Access Program for Convalescent Plasma reference materials.

Review historical documents

Program highlights

  • A review and meta-analysis of transfusing COVID-19 high-titer plasma to treat immunocompromised patients has been published. Read the review.


    High titer convalescent plasma has received Emergency Use Authorization from the US FDA to treat immunocompromised patients.

    How to order and administer

  • Convalescent plasma evidence update

    An update on the safety, access and efficacy of convalescent plasma to treat COVID-19 has been added in the Physicians section. Read the report.

  • Program closure

    On May 1, 2022, the Expanded Access Program (EAP) for Convalescent Plasma ended. This planned closure concludes a successful program. Thanks to all participating locations and providers. The EAP team continues to analyze program data, author publications and provide education. New papers and presentations are posted on this website. Until further notice, the team will monitor and respond within five business days.

  • Mayo Clinic has authored a Wikipedia page on convalescent plasma (CP) that includes an overview of CP, a graphical representation of how it works, and historical and modern use of CP as a therapy for a number of infectious diseases.
  • Stay up-to-date on the National COVID-19 Convalescent Plasma Project, including news, key scientific papers, donor stories and ongoing clinical trials.
  • included in national archive

    The website is in the nation's historic Coronavirus Web Archive due to the importance of the Expanded Access Program in response to the pandemic and Mayo Clinic's leadership role. Archived information is on their public access website.

Historical EAP program participation

Participating locations and enrolled providers

  • Sites
  • Physicians
  • Patients
  • Infused